![]() ![]() Some interventions like exercise or antidepressant administration enhance the expression of BDNF in normal and pathological conditions. Changes in BDNF expression are associated with both normal and pathological aging and also psychiatric disease, in particular in structures important for memory processes such as the hippocampus and parahippocampal areas. The expression of BDNF is highly regulated, and can lead to great variability in BDNF levels in healthy subjects. Laboratory of Memory Research and Molecular Cognition, Institute for Cognitive and Translational Neuroscience, Instituto de Neurología Cognitiva, CONICET, Universidad Favaloro, Buenos Aires, Argentinaīrain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes related to learning and memory.Magdalena Miranda, Juan Facundo Morici, María Belén Zanoni and Pedro Bekinschtein *
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